A look at the protective effects of coffee, tea, and caffeine consumption on cardiometabolic health.

Caffeine is linked to Heart Disease Risk in Some: Does it in You?

Habitual coffee or caffeine intake, especially at a moderate level, was associated with a lower risk of new-onset CM.

We have developed novel caffeine derivatives that markedly reduce PCSK9 expression/secretion.

Members of Systemic Therapeutics attended the Stanford Drug Discovery Symposium 2024 from April 29 - 30.

This study demonstrates that the neuroprotection of coffee on PD is attributed to caffeine and its metabolites.

In hepatocytes, caffeine is known to suppress SREBF2 activity, which reduces PCSK9 expression, and thus increases LDLR expression

This ground-breaking research suggested that PCSK9 could degrade CD36

coffee components can influence lipid and cancer metabolism by regulating adipogenesis and carcinogenesis

caffeine has been demonstrated to enhance hepatic ER-linked Ca2+ levels and inhibit the transcriptional activation of SREBP2